The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/2000. Detects a band of approximately 45 kDa (predicted molecular weight: 38 kDa).
1/250. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Expressed in various cancer cell ines.
Belongs to the SDS3 family.
The C-terminus is involved in transcriptional repression by HDAC-independent mechanisms.
Flow cytometric analysis of 2% paraformaldehyde-fixed HeLa cells labeling SDS3 with ab184555 at 1/250 dilution (red) compared to a Rabbit monoclonal isotype control (green), followed by Goat anti-rabbit IgG (FITC) secondary antibody at 1/150 dilution.