Anti-SEC24B antibody (ab122445)
Key features and details
- Rabbit polyclonal to SEC24B
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SEC24B antibody -
Description
Rabbit polyclonal to SEC24B -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence: SFQGAASSAS HLHTSASQPY SSFVNHYNSP AMYSASSSVA SQGFPSTCGH YAMSTVSNAA YPSVSYPSLP AGDTYGQMFT SQNAPTVR, corresponding to amino acids 133-220 of Human SEC24B
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Positive control
- IHC: Human kidney tissue ICC/IF: Human cell line A-431
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122445 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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IHC-P |
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. -
Tissue specificity
Expressed in fibroblasts, hepatocytes, and lymphocytes. -
Sequence similarities
Belongs to the SEC23/SEC24 family. SEC24 subfamily. -
Cellular localization
Cytoplasm. Cytoplasm > perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane. Golgi apparatus membrane. - Information by UniProt
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Database links
- Entrez Gene: 10427 Human
- Omim: 607184 Human
- SwissProt: O95487 Human
- Unigene: 292472 Human
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Alternative names
- Protein transport protein Sec24B antibody
- SC24B_HUMAN antibody
- SEC24 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab122445 has not yet been referenced specifically in any publications.