Overview

  • Product nameAnti-SEC24D antibody
    See all SEC24D primary antibodies
  • Description
    Rabbit polyclonal to SEC24D
  • Tested applicationsSuitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: ASQLILPDSM KVLPVYMNCL LKNCVLLSRP EISTDERAYQ RQLVMTMGVA DSQLFFYPQL LPIHTLDVKS TMLPAAVRCS ESRLS, corresponding to amino acids 830-914 of Human SEC24D.

  • Positive control
    • Human pancreas tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab122732 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

Target

  • FunctionComponent of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
  • Tissue specificityUbiquitously expressed, with higher amounts in placenta, pancreas, heart and liver.
  • Sequence similaritiesBelongs to the SEC23/SEC24 family. SEC24 subfamily.
  • Cellular localizationCytoplasm. Cytoplasm > perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA0755 antibody
    • Protein transport protein Sec24D antibody
    • SC24D_HUMAN antibody
    • SEC24 family member D antibody
    • SEC24 related gene family, member D antibody
    • SEC24-related protein D antibody
    • SEC24D antibody
    see all

Anti-SEC24D antibody images

  • Immunofluorescent staining of Human cell line A-431 shows positivity in nucleus but not nucleoli. Recommended concentration of ab122732 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122732 at 1/1000 dilution staining SEC24D in Paraffin-embedded Human pancreas by Immunohistochemistry.

References for Anti-SEC24D antibody (ab122732)

ab122732 has not yet been referenced specifically in any publications.

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