Overview

  • Product name
    Anti-SEC31B antibody
  • Description
    Rabbit polyclonal to SEC31B
  • Specificity
    This antibody reacts specifically with human 128 kDa SEC31B protein.
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, a wide range of other species
  • Immunogen

    Synthetic peptide derived from the N terminal domain of Human SEC31B

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: None
    Constituents: Whole serum
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab80053 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/500 - 1/5000. Predicted molecular weight: 129 kDa.

Target

  • Function
    As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.
  • Tissue specificity
    Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular cells (at protein level).
  • Sequence similarities
    Belongs to the WD repeat SEC31 family.
    Contains 8 WD repeats.
  • Post-translational
    modifications
    Monoubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex, leading to regulate the size of COPII coats.
  • Cellular localization
    Cytoplasm. Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • SEC31L2 antibody
    • Gm341 antibody
    • Protein transport protein Sec31B antibody
    • SC31B_HUMAN antibody
    • SEC31 B antibody
    • SEC31 homolog B (S. cerevisiae) antibody
    • SEC31 homolog B antibody
    • SEC31 like 2 antibody
    • SEC31 related protein B antibody
    • SEC31-like protein 2 antibody
    • SEC31-related protein B antibody
    • SEC31B 1 antibody
    • SEC31B antibody
    • SEC31B-1 antibody
    • Secretory pathway component Sec31B 1 antibody
    • secretory pathway component Sec31B1 antibody
    see all

References for Anti-SEC31B antibody (ab80053)

ab80053 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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