Overview

  • Product nameAnti-SEC63 antibody
    See all SEC63 primary antibodies
  • Description
    Mouse polyclonal to SEC63
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length SEC63 protein (Human) (NP_009145.1).

  • Positive control
    • Human pancreas lysate, SEC63 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab68550 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 88 kDa (predicted molecular weight: 88 kDa).

Target

  • RelevanceSEC63 and SEC62 proteins are found to be associated with the ribosome-free SEC61 complex, which is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Mutations in SEC63 cause autosomal dominant polycystic liver disease.
  • Cellular localizationEndoplasmic reticulum membrane; Multi pass membrane protein.
  • Database links
  • Alternative names
    • ERdj2 antibody
    • PRO2507 antibody
    • SEC 63 antibody
    • SEC63L antibody
    • Translocation protein SEC63 homolog antibody
    see all

Anti-SEC63 antibody images

  • Anti-SEC63 antibody (ab68550) at 1/500 dilution + Human pancreas lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L) at 1/2500 dilution

    Predicted band size : 88 kDa
    Observed band size : 88 kDa
  • All lanes : Anti-SEC63 antibody (ab68550) at 1/500 dilution

    Lane 1 : SEC63 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L) at 1/2500 dilution

    Predicted band size : 88 kDa
    Observed band size : 88 kDa

References for Anti-SEC63 antibody (ab68550)

ab68550 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab68550.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"