Overview

  • Product name
    Anti-SECISBP2 antibody [2957C2a]
    See all SECISBP2 primary antibodies
  • Description
    Mouse monoclonal [2957C2a] to SECISBP2
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment of human SECISBP2 derived from a near N terminal internal sequence.

  • Positive control
    • HEK293 whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab70601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 2 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 95 kDa).
Dot blot Use at an assay dependent dilution.

Target

  • Function
    Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
  • Tissue specificity
    Expressed at high levels in testis.
  • Involvement in disease
    Defects in SECISBP2 are a cause of abnormal thyroid hormone metabolism (ATHYHM) [MIM:609698]. This phenotype is associated with a reduction in type II iodothyronine deiodinase activity.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686C09169 antibody
    • OTTHUMP00000064929 antibody
    • OTTHUMP00000064930 antibody
    • OTTHUMP00000064931 antibody
    • OTTHUMP00000064932 antibody
    • RP11 89K14.1 antibody
    • SBP 2 antibody
    • SBP2 antibody
    • SEBP2_HUMAN antibody
    • SECIS binding protein 2 antibody
    • SECIS-binding protein 2 antibody
    • SECISBP 2 antibody
    • SECISBP2 antibody
    • Selenocysteine insertion sequence binding protein 2 antibody
    • Selenocysteine insertion sequence-binding protein 2 antibody
    see all

Images

  • Anti-SECISBP2 antibody [2957C2a] (ab70601) at 2 µg/ml + HEK293 whole cell lysate at 25 µg
    Developed using the ECL technique

    Predicted band size : 95 kDa
    Observed band size : 105 kDa (why is the actual band size different from the predicted?)

References

ab70601 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab70601.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up