Anti-Secretory phospholipase A2 Type V antibody (ab118496)

Overview

  • Product name
    Anti-Secretory phospholipase A2 Type V antibody
    See all Secretory phospholipase A2 Type V primary antibodies
  • Description
    Rabbit polyclonal to Secretory phospholipase A2 Type V
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    CAIRTQSYDYRYTNGL

    conjugated to KLH, corresponding to internal sequence amino acids 79-94 of Mouse Secretory phospholipase A2 Type V.

  • Positive control
    • Human Skeletal Muscle

Properties

Applications

Our Abpromise guarantee covers the use of ab118496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 16 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L-alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L-alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle.
  • Tissue specificity
    Heart, placenta and less abundantly, in lung.
  • Sequence similarities
    Belongs to the phospholipase A2 family.
  • Post-translational
    modifications
    This enzyme lacks one of the seven disulfide bonds found in similar PA2 proteins.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ca2+ dependent phospholipase A2 antibody
    • Calcium dependent phospholipase A2 antibody
    • Calcium-dependent phospholipase A2 antibody
    • DKFZp686C2294 antibody
    • FRFB antibody
    • Group V phospholipase A2 antibody
    • GV PLA2 antibody
    • gVPLA2 antibody
    • hVPLA(2) antibody
    • MGC46205 antibody
    • OTTHUMP00000044655 antibody
    • PA2G5_HUMAN antibody
    • Phosphatidylcholine 2 acylhydrolase antibody
    • Phosphatidylcholine 2-acylhydrolase 5 antibody
    • Phospholipase A2 group V antibody
    • PLA2 10 antibody
    • PLA2 G5 antibody
    • PLA2-10 antibody
    • Pla2g5 antibody
    • sPLA2 Type V antibody
    see all

Images

  • ab118496 at 10 µg/ml staining Secretory phospholipase A2 Type V in Human Skeletal Muscle by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

References

ab118496 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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