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ab3305 has been referenced in 39 publications.

  • Heikkinen I  et al. Does securin expression have significance in prognostication of oral tongue cancer? A pilot study. Eur Arch Otorhinolaryngol 273:3905-3911 (2016). PubMed: 27091335
  • Kurkalang S  et al. Precocious anaphase and expression of Securin and p53 genes as candidate biomarkers for the early detection in areca nut-induced carcinogenesis. Mutagenesis 30:381-9 (2015). PubMed: 25480871
  • Bailey ML  et al. Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. Genetics 201:885-95 (2015). WB ; Human . PubMed: 26354767
  • Zhou C  et al. PTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility. Oncogene 33:851-61 (2014). WB, IHC-P ; Human . PubMed: 23416975
  • Kung PP  et al. Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer. Mol Cancer Ther 13:2104-15 (2014). PubMed: 24928852
  • Adhikari D  et al. Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II. J Cell Biol 206:843-53 (2014). Mouse . PubMed: 25246615
  • Nabti I  et al. Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity. J Cell Biol 204:891-900 (2014). WB . PubMed: 24637322
  • Trakala M  et al. Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1). Cell Cycle 12:1030-41 (2013). WB ; Mouse . PubMed: 23428904
  • Zhou L  et al. The role of RING box protein 1 in mouse oocyte meiotic maturation. PLoS One 8:e68964 (2013). PubMed: 23874827
  • Listovsky T & Sale JE Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset. J Cell Biol 203:87-100 (2013). Human . PubMed: 24100295
  • Yu Y & Munger K Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis. Virology 446:251-9 (2013). PubMed: 24074588
  • Tseng HH  et al. Securin Enhances the Anti-Cancer Effects of 6-Methoxy-3-(3',4',5'-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in Human Colorectal Cancer Cells. PLoS One 7:e36006 (2012). WB ; Human . PubMed: 22563433
  • Holt JE  et al. The APC/C activator FZR1 coordinates the timing of meiotic resumption during prophase I arrest in mammalian oocytes. Development 138:905-13 (2011). PubMed: 21270054
  • Chang HY  et al. Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720. J Biol Chem 286:14705-12 (2011). PubMed: 21383018
  • Kannan RP  et al. Hepatitis C virus infection causes cell cycle arrest at the level of initiation of mitosis. J Virol 85:7989-8001 (2011). WB ; Human . PubMed: 21680513
  • Olsen JV  et al. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3:ra3 (2010). PubMed: 20068231
  • Dulla K  et al. Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics 9:1167-81 (2010). WB ; Human . PubMed: 20097925
  • Keppner S  et al. Biological impact of freezing Plk1 in its inactive conformation in cancer cells. Cell Cycle 9:761-73 (2010). WB ; Human . PubMed: 20139717
  • van Zon W  et al. The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit. J Cell Biol 190:587-602 (2010). PubMed: 20733055
  • Huang YT  et al. TrkB antibody elicits cytotoxicity and suppresses migration/invasion of transitional cell carcinoma cells. Int J Oncol 37:943-9 (2010). PubMed: 20811716
  • van Ree JH  et al. Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation. J Cell Biol 188:83-100 (2010). WB ; Mouse . PubMed: 20065091
  • Gurden MD  et al. Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. J Cell Sci 123:321-30 (2010). WB ; Human . PubMed: 20053638
  • Zhou C  et al. E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors. Mol Endocrinol 23:2000-12 (2009). PubMed: 19837943
  • Gaitanos TN  et al. Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. EMBO J 28:1442-52 (2009). WB ; Human . PubMed: 19360002
  • Talvinen K  et al. Securin promotes the identification of favourable outcome in invasive breast cancer. Br J Cancer 101:1005-10 (2009). PubMed: 19690544
  • Marangos P & Carroll J Securin regulates entry into M-phase by modulating the stability of cyclin B. Nat Cell Biol 10:445-51 (2008). WB, ICC/IF ; Mouse . PubMed: 18364698
  • Talvinen K  et al. Proliferation marker securin identifies favourable outcome in invasive ductal breast cancer. Br J Cancer 99:335-40 (2008). IHC-P ; Human . PubMed: 18594525
  • Qiao D  et al. Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells. Mol Biol Cell 19:2789-801 (2008). WB ; Mouse . PubMed: 18417614
  • Lee SH  et al. Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint. Genes Dev 22:2926-31 (2008). IP ; Human . PubMed: 18981471
  • Niault T  et al. Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I. PLoS ONE 2:e1165 (2007). WB ; Mouse . PubMed: 18043727
  • Ngo TT  et al. The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas. J Natl Cancer Inst 99:639-52 (2007). PubMed: 17440165
  • Liu CL  et al. L2dtl is essential for cell survival and nuclear division in early mouse embryonic development. J Biol Chem 282:1109-18 (2007). PubMed: 17107960
  • Reis A  et al. Prometaphase APCcdh1 activity prevents non-disjunction in mammalian oocytes. Nat Cell Biol 9:1192-8 (2007). WB ; Mouse . PubMed: 17891138
  • Keck JM  et al. Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). J Cell Biol 178:371-85 (2007). WB ; Human . PubMed: 17664332
  • Chao JI  et al. Depletion of Securin Increases Arsenite-Induced Chromosome Instability and Apoptosis via a p53-Independent Pathway. Toxicol Sci 90:73-86 (2006). PubMed: 16338954
  • Chao JI & Liu HF The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells. Mol Pharmacol 69:154-64 (2006). PubMed: 16219911
  • Huo LJ  et al. Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition. Front Biosci 11:2193-202 (2006). PubMed: 16720305
  • Holland AJ & Taylor SS Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction. J Cell Sci 119:3325-36 (2006). ICC/IF . PubMed: 16868023
  • Chen Z  et al. A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth. Mol Cancer Ther 4:562-8 (2005). PubMed: 15827329

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