The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesPeptide ELISA: Antibody detection limit dilution 1/4000.
WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 88 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionMay play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.
Tissue specificityHighly expressed in pancreas.
Sequence similaritiesBelongs to the sel-1 family. Contains 1 fibronectin type-II domain. Contains 11 Sel1-like repeats.