Overview

  • Product nameAnti-Selenoprotein M antibody [10C1]
    See all Selenoprotein M primary antibodies
  • Description
    Mouse monoclonal [10C1] to Selenoprotein M
  • Tested applicationsSuitable for: ELISA, WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human) purified from E coli

Properties

Applications

Our Abpromise guarantee covers the use of ab16960 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IP
  • Application notesELISA: Use at an assay dependent dilution.
    IP: Use at a concentration of 1 - 2 µg/ml lysates.
    WB: 1/2000. Predicted molecular weight: 16 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceSelenoprotein M is widely expressed and expressed highly in the mammalian brain. It is localized to the perinuclear structures (Golgi/ER). A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in antioxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/disulfide exchange. The roles of Selenoprotein M have not been clearly identified until present time.
    • Cellular localizationCytoplasm; perinuclear region. Endoplasmic reticulum Probable. Golgi apparatus Probable. Note: Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum.
    • Database links
    • Alternative names
      • Selenoprotein M antibody
      • Selenoprotein SelM antibody
      • SELM antibody
      • SelM protein antibody
      • SEPM antibody
      see all

    References for Anti-Selenoprotein M antibody [10C1] (ab16960)

    This product has been referenced in:
    • Xu G  et al. The relationship between deiodinase activity and inflammatory responses under the stimulation of uremic toxins. J Transl Med 12:239 (2014). WB ; Human . Read more (PubMed: 25174507) »
    • Goo JS  et al. Proteomic analysis of kidneys from selenoprotein M transgenic rats in response to increased bioability of selenium. Clin Proteomics 10:10 (2013). WB ; Rat . Read more (PubMed: 23937859) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"