Overview

  • Product nameAnti-SELS antibody
    See all SELS primary antibodies
  • Description
    Mouse polyclonal to SELS
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human SELS protein (NP_060915.2).

  • Positive control
    • A431 cell lysate. Cell lysate from transfected 293T cells.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab89760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).

Target

  • RelevanceInvolved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
  • Cellular localizationEndoplasmic reticulum; endoplasmic reticulum membrane; single pass membrane protein.
  • Database links
  • Alternative names
    • AD-015 antibody
    • ADO15 antibody
    • MGC104346 antibody
    • MGC2553 antibody
    • SBBI8 antibody
    • selenoprotein S antibody
    • SEPS1 antibody
    • VCP interacting membrane protein antibody
    • VCP-interacting membrane antibody
    • VIMP antibody
    see all

Anti-SELS antibody images

  • Anti-SELS antibody (ab89760) at 1 µg/ml + A431 cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 21 kDa
    Observed band size : ~20 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-SELS antibody (ab89760) at 1 µg/ml

    Lane 1 : cell lysate from SELS transfected 293T cells
    Lane 2 : cell lysate from non transfected 293T cells

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 21 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)

References for Anti-SELS antibody (ab89760)

ab89760 has not yet been referenced specifically in any publications.

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