• Product name
    Anti-Sema6A antibody - C-terminal
    See all Sema6A primary antibodies
  • Description
    Rabbit polyclonal to Sema6A - C-terminal
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide from the C-terminal region of human Sema6A conjugated to KLH

  • Positive control
    • Mouse cerebellum tissue lysate.



Our Abpromise guarantee covers the use of ab72369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 97 kDa (predicted molecular weight: 114 kDa).
ELISA 1/1000.
IHC-P 1/10 - 1/50.


  • Function
    Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
  • Sequence similarities
    Belongs to the semaphorin family.
    Contains 1 PSI domain.
    Contains 1 Sema domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • HT018 antibody
    • SEM6A_HUMAN antibody
    • SEMA antibody
    • Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A antibody
    • Sema Q antibody
    • Sema VIA antibody
    • SEMA6A 1 antibody
    • Sema6a antibody
    • SEMA6A-1 antibody
    • SEMA6A1 antibody
    • Semaphorin 6A 1 antibody
    • Semaphorin Q antibody
    • Semaphorin VIA antibody
    • Semaphorin-6A antibody
    • Semaphorin-6A-1 antibody
    • SEMAQ antibody
    • VIA antibody
    see all


  • All lanes : Anti-Sema6A antibody - C-terminal (ab72369) at 1/50 dilution

    Lane 1 : Mouse cerebellum tissue lysate
    Lane 2 : Mouse cerebellum tissue lysate with blocking peptide

    Lysates/proteins at 12.5 µg per lane.

    Predicted band size : 114 kDa
    Observed band size : 97 kDa (why is the actual band size different from the predicted?)
  • ab72369 at 1/50 dilution staining Sema6A - C - terminal in human brain tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections). A peroxidase conjugated secondary antibody was used followed by DAB staining.


This product has been referenced in:
  • Lee MY  et al. Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells. Cell Div 9:3 (2014). WB ; Human . Read more (PubMed: 25278993) »
  • Sabag AD  et al. The role of the plexin-A2 receptor in Sema3A and Sema3B signal transduction. J Cell Sci 127:5240-52 (2014). Read more (PubMed: 25335892) »

See all 2 Publications for this product

Customer reviews and Q&As

Thank you for your enquiry and interest in our products.

I can confirm that this product (ab72369: Anti-Sema6A antibody - C-terminal) was launched in 2008.

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