Overview

  • Product nameAnti-SEMA6C antibody
    See all SEMA6C primary antibodies
  • Description
    Mouse polyclonal to SEMA6C
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    SEMA6C (NP_112175, 1 a.a. ~ 930 a.a) full-length human protein.

  • Positive control
    • SEMA6C transfected 293T lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab68471 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 130 kDa (predicted molecular weight: 100 kDa).

Target

  • RelevanceSEMA6C belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. SEMA6C shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro and may be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. SEMA6C may also be involved in the maintenance and remodeling of neuronal connections.
  • Cellular localizationMembrane; Single-pass type I membrane protein.
  • Database links
  • Alternative names
    • KIAA1869 antibody
    • m Sema Y antibody
    • m Sema Y2 antibody
    • sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C antibody
    • Sema Y antibody
    • Semaphorin 6C [Precursor] antibody
    • Semaphorin Y antibody
    • SEMAY antibody
    see all

Anti-SEMA6C antibody images

  • All lanes : Anti-SEMA6C antibody (ab68471) at 1/500 dilution

    Lane 1 : SEMA6C transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 100 kDa
    Observed band size : 130 kDa (why is the actual band size different from the predicted?)

References for Anti-SEMA6C antibody (ab68471)

ab68471 has not yet been referenced specifically in any publications.

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