Anti-Semaphorin 3A antibody - N-terminal (ab226793)

Overview

  • Product name
    Anti-Semaphorin 3A antibody - N-terminal
    See all Semaphorin 3A primary antibodies
  • Description
    Rabbit polyclonal to Semaphorin 3A - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Chicken, Cow
  • Immunogen

    Recombinant fragment within Human Semaphorin 3A (N terminal). The exact sequence is proprietary.
    Database link: Q14563

  • Positive control
    • WB: U-87 MG, SK-N-SH, IMR32 and SK-N-AS whole cell lysates. IHC-P: Mouse brain tissue; rat duodenum tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab226793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 89 kDa.

Target

  • Relevance
    One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI anchored extracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co receptors, Neuropilin 1 and Plexin A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A containing region. Thus, Sema3A and its co receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • Coll 1 antibody
    • Coll1 antibody
    • Collapsin 1 antibody
    • HH16 antibody
    • Hsema I antibody
    • Hsema III antibody
    • Sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3A antibody
    • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A antibody
    • Sema III antibody
    • SEMA1 antibody
    • SEMA1-PEN antibody
    • SEMA3A antibody
    • SEMAD antibody
    • SEMAIII antibody
    • SEMAL antibody
    • Semaphorin 3A precursor antibody
    • Semaphorin III antibody
    • semaphorin L antibody
    • Semaphorin like growth cone guidance homolog of chick collapsin antibody
    • Semaphorin-D antibody
    • Semaphorin3A antibody
    • SemD antibody
    see all

Images

  • All lanes : Anti-Semaphorin 3A antibody - N-terminal (ab226793) at 1/500 dilution

    Lane 1 : U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell lysate
    Lane 2 : SK-N-SH (human neuroblastoma cell line) whole cell lysate
    Lane 3 : IMR32 (human neuroblastoma cell line) whole cell lysate
    Lane 4 : SK-N-AS (human neuroblastoma cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 89 kDa

  • Paraffin-embedded mouse brain tissue stained for Semaphorin 3A with ab226793 at 1/500 dilution in immunohistochemical analysis.

  • Paraffin-embedded rat duodenum tissue stained for Semaphorin 3A with ab226793 at 1/500 dilution in immunohistochemical analysis.

References

ab226793 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab226793.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up