Overview

  • Product name
    Anti-Semaphorin 4D antibody [A8]
    See all Semaphorin 4D primary antibodies
  • Description
    Mouse monoclonal [A8] to Semaphorin 4D
  • Tested applications
    Suitable for: IP, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human PHA activated lymphocytes

  • Positive control
    • Human lymphocytes.

Properties

Applications

Our Abpromise guarantee covers the use of ab86829 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
Flow Cyt Use 0.25µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Function
    May play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.
  • Tissue specificity
    Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.
  • Sequence similarities
    Belongs to the semaphorin family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 PSI domain.
    Contains 1 Sema domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • A8 antibody
    • BB 18 antibody
    • BB18 antibody
    • CD 100 antibody
    • CD100 antibody
    • CD100 antigen antibody
    • Coll 4 antibody
    • COLL4 antibody
    • Collapsin 4 antibody
    • Collapsin4 antibody
    • GR3 antibody
    • Leukocyte activation antigen CD100 antibody
    • M sema G antibody
    • MSEMA antibody
    • SEM4D_HUMAN antibody
    • Sema 4d antibody
    • Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D antibody
    • Sema H antibody
    • SEMA J antibody
    • Sema4d antibody
    • Semacl 2 antibody
    • Semacl2 antibody
    • SemaH antibody
    • SEMAJ antibody
    • Semaphorin 4D antibody
    • Semaphorin C like 2 antibody
    • Semaphorin H antibody
    • Semaphorin J antibody
    • Semaphorin-4D antibody
    • Semaphorin4D antibody
    • SemaphorinJ antibody
    • Semcl 2 antibody
    • Semcl2 antibody
    see all

Images

  • Cell surface flow cytometric analysis of Semaphorin 4D in human lymphocytes using ab86829 at 0.25 ug/106 cells. Shaded histogram represents cells without antibody; green represents isotype control; red represents ab86829. A Goat anti-mouse IgG PE conjugated secondary was used in this test.

References

This product has been referenced in:
  • Hall KT  et al. Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation. Proc Natl Acad Sci U S A 93:11780-5 (1996). Read more (PubMed: 8876214) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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