Anti-Semaphorin 4D antibody (ab46959)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab46959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 117 kDa (predicted molecular weight: 96 kDa).
IHC-P Use at an assay dependent concentration.

Target

  • FunctionMay play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.
  • Tissue specificityStrongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.
  • Sequence similaritiesBelongs to the semaphorin family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 PSI domain.
    Contains 1 Sema domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • A8 antibody
    • BB 18 antibody
    • BB18 antibody
    • CD 100 antibody
    • CD100 antibody
    • CD100 antigen antibody
    • Coll 4 antibody
    • COLL4 antibody
    • Collapsin 4 antibody
    • Collapsin4 antibody
    • GR3 antibody
    • Leukocyte activation antigen CD100 antibody
    • M sema G antibody
    • MSEMA antibody
    • SEM4D_HUMAN antibody
    • Sema 4d antibody
    • Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D antibody
    • Sema H antibody
    • SEMA J antibody
    • Sema4d antibody
    • Semacl 2 antibody
    • Semacl2 antibody
    • SemaH antibody
    • SEMAJ antibody
    • Semaphorin 4D antibody
    • Semaphorin C like 2 antibody
    • Semaphorin H antibody
    • Semaphorin J antibody
    • Semaphorin-4D antibody
    • Semaphorin4D antibody
    • SemaphorinJ antibody
    • Semcl 2 antibody
    • Semcl2 antibody
    see all

Anti-Semaphorin 4D antibody images

References for Anti-Semaphorin 4D antibody (ab46959)

ab46959 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (Brain)
Specification Brain
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Citrate pH6
Permeabilization No
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: RT°C
Username

Mr. Manoj Kumar Valluru

Verified customer

Submitted Jun 03 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"