Overview

  • Product nameAnti-Semaphorin 5A antibody
    See all Semaphorin 5A primary antibodies
  • Description
    Rabbit polyclonal to Semaphorin 5A
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    a KLH conjugated synthetic peptide selected from the C-terminal region of mouse Semaphorin 5A

Properties

Applications

Our Abpromise guarantee covers the use of ab70981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 100 kDa (predicted molecular weight: 120 kDa).
ELISA 1/1000.

Target

  • RelevanceMembers of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.
  • Cellular localizationMembrane; single-pass type I membrane protein
  • Database links
  • Alternative names
    • SEMA5A antibody
    • SEMAF antibody
    • Semaphorin F antibody

Anti-Semaphorin 5A antibody images

  • Anti-Semaphorin 5A antibody (ab70981) at 1/60 dilution + mouse brain lysate at 35 µg

    Predicted band size : 120 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 80 kDa,95 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Semaphorin 5A antibody (ab70981)

ab70981 has not yet been referenced specifically in any publications.

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