Anti-Semaphorin 5A antibody - N-terminal (ab75725)

Overview

  • Product nameAnti-Semaphorin 5A antibody - N-terminal
    See all Semaphorin 5A primary antibodies
  • Description
    Rabbit polyclonal to Semaphorin 5A - N-terminal
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    KLH conjugated synthetic peptide selected from the N-terminal region of human Semaphorin 5A.

  • Positive control
    • A2058 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab75725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 120 kDa.
ELISA 1/1000.

Target

  • RelevanceMembers of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.
  • Cellular localizationMembrane; single-pass type I membrane protein
  • Database links
  • Alternative names
    • SEMA5A antibody
    • SEMAF antibody
    • Semaphorin F antibody

Anti-Semaphorin 5A antibody - N-terminal images

References for Anti-Semaphorin 5A antibody - N-terminal (ab75725)

ab75725 has not yet been referenced specifically in any publications.

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