Anti-Semaphorin 7a antibody [MM0537-99D22] (ab90242)

Overview

  • Product nameAnti-Semaphorin 7a antibody [MM0537-99D22]
    See all Semaphorin 7a primary antibodies
  • Description
    Rat monoclonal [MM0537-99D22] to Semaphorin 7a
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: , corresponding to amino acids 46-645 of Human Semaphorin 7a

Properties

Applications

Our Abpromise guarantee covers the use of ab90242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Predicted molecular weight: 75 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPlays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
    • Tissue specificityDetected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level). Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney.
    • Sequence similaritiesBelongs to the semaphorin family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 PSI domain.
      Contains 1 Sema domain.
    • Cellular localizationCell membrane. Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 108 antibody
      • CD108 antibody
      • CD108 antigen antibody
      • CDw108 antibody
      • H Sema K1 antibody
      • H Sema L antibody
      • H-SEMA-K1 antibody
      • H-Sema-L antibody
      • JMH antibody
      • JMH blood group antigen antibody
      • John Milton Hagen blood group H Sema K1 antibody
      • John Milton Hargen human blood group Ag antibody
      • John-Milton-Hargen human blood group Ag antibody
      • MGC126692 antibody
      • MGC126696 antibody
      • SEM7A_HUMAN antibody
      • Sema domain immunoglobulin domain (Ig) and GPI membrane anchor 7A antibody
      • Sema K1 antibody
      • Sema L antibody
      • SEMA7A antibody
      • SEMAK1 antibody
      • SEMAL antibody
      • Semaphorin 7A GPI membrane anchor antibody
      • Semaphorin K1 antibody
      • Semaphorin L antibody
      • Semaphorin-7A antibody
      • Semaphorin-K1 antibody
      • Semaphorin-L antibody
      • Semaphorin7a antibody
      see all

    Anti-Semaphorin 7a antibody [MM0537-99D22] images

    • Anti-Semaphorin 7a antibody [MM0537-99D22] (ab90242) at 1/500 dilution + Human brain tissue

      Predicted band size : 75 kDa

    References for Anti-Semaphorin 7a antibody [MM0537-99D22] (ab90242)

    ab90242 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us.

    I have had the opportunity to speak with the lab. The Western blot was tested using the immunogen (extracellular domain of the human protein), with antibody concentration around 1microgram/ml,. Unfortunately do n...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"