Anti-SENP5 antibody (ab58420)
Key features and details
- Rabbit polyclonal to SENP5
- Suitable for: WB, IHC-P
- Reacts with: Human, African green monkey
- Isotype: IgG
Overview
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Product name
Anti-SENP5 antibody -
Description
Rabbit polyclonal to SENP5 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human, African green monkey -
Immunogen
Synthetic peptide corresponding to Human SENP5 aa 651-700.
Database link: Q96HI0 -
Positive control
- IHC-P: Human lung carcinoma. WB: Cos-7 cell extract.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg+2 and Ca+2 -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab58420 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (2) |
Use at an assay dependent concentration. Detects a band of approximately 87 kDa (predicted molecular weight: 87 kDa).
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IHC-P |
Use at an assay dependent concentration.
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Notes |
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WB
Use at an assay dependent concentration. Detects a band of approximately 87 kDa (predicted molecular weight: 87 kDa). |
IHC-P
Use at an assay dependent concentration. |
Target
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Function
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. -
Sequence similarities
Belongs to the peptidase C48 family. -
Cellular localization
Nucleus > nucleolus. - Information by UniProt
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Database links
- Entrez Gene: 205564 Human
- Omim: 612845 Human
- SwissProt: Q96HI0 Human
- Unigene: 240770 Human
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Alternative names
- FKSG45 antibody
- FLJ42398 antibody
- MGC27076 antibody
see all
Images
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Immunohistochemical analysis of paraffin embedded human lung carcinoma using ab58420 at 1/50 dilution, in the absence or presence of the immunizing peptide.
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All lanes : Anti-SENP5 antibody (ab58420) at 1/500 dilution
Lane 1 : Cos 7 cell extract
Lane 2 : Cos 7 cell extract with immunizing peptide
Predicted band size: 87 kDa
Observed band size: 87 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab58420 has been referenced in 2 publications.
- Zhang X et al. Zinc deficiency induces abnormal development of the myocardium by promoting SENP5 overexpression. PLoS One 15:e0242606 (2020). PubMed: 33211757
- Culver C et al. Mechanism of hypoxia-induced NF-kappaB. Mol Cell Biol 30:4901-21 (2010). WB ; Human . PubMed: 20696840