Overview

  • Product nameAnti-SENP8 antibody
    See all SENP8 primary antibodies
  • Description
    Rabbit polyclonal to SENP8
  • Specificityab58423 detects endogenous levels of total SENP8 protein.
  • Tested applicationsSuitable for: ELISA, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from an internal of human SENP8.

  • Positive control
    • Human breast carcinoma tissue and HuvEc cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab58423 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/10000.
IHC-P Use at an assay dependent concentration.
WB 1/500 - 1/1000. Predicted molecular weight: 24 kDa.

Target

  • FunctionProtease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
  • Tissue specificityBroadly expressed, with highest levels in kidney and pancreas.
  • Sequence similaritiesBelongs to the peptidase C48 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • cysteine 2 antibody
    • DEN 1 antibody
    • DEN1 antibody
    • Deneddylase 1 antibody
    • Deneddylase-1 antibody
    • FKSG8 antibody
    • HsT17512 antibody
    • NEDD 8 specific protease 1 antibody
    • NEDD8 specific protease cysteine 2 antibody
    • NEDD8-specific protease 1 antibody
    • NEDP 1 antibody
    • NEDP1 antibody
    • Protease antibody
    • Protease, cysteine 2 antibody
    • PRSC2 antibody
    • SENP8 antibody
    • SENP8_HUMAN antibody
    • Sentrin / SUMO specific protease SENP 8 antibody
    • Sentrin-specific protease 8 antibody
    • Sentrin/SUMO-specific protease SENP8 antibody
    • SUMO sentrin specific protease family member 8 antibody
    • SUMO/sentrin peptidase family member, NEDD8 specific antibody
    • SUMO/sentrin specific peptidase family member 8 antibody
    see all

Anti-SENP8 antibody images

  • ab58423 at 1/50 dilution staining SENP8 in human breast carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.
  • All lanes : Anti-SENP8 antibody (ab58423) at 1/500 dilution

    Lane 1 : HuvEc cell extract
    Lane 2 : HuvEc cell extract with immunizing peptide


    Predicted band size : 24 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)

References for Anti-SENP8 antibody (ab58423)

ab58423 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"