• Product nameAnti-SEPT6 antibody
    See all SEPT6 primary antibodies
  • Description
    Goat polyclonal to SEPT6
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog
  • Immunogen

    Synthetic peptide:


    by a Cysteine residue linker, corresponding to C terminal amino acids 391-402 of Human SEPT6 (NP_665798.1; NP_055944.2; NP_665801.1).

  • Positive control
    • Human testis, thyroid gland and MOLT4 cell lysates
  • General notes

    ab106924 is expected to recognize the reported isoforms NP_665798.1, NP_055944.2 and NP_665801.1. Reported variants NP_665799.1 and NP_665798.1 represent identical protein.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Primary antibody notesab106924 is expected to recognize the reported isoforms NP_665798.1, NP_055944.2 and NP_665801.1. Reported variants NP_665799.1 and NP_665798.1 represent identical protein.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab106944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 50 kDa.


  • FunctionFilament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesBelongs to the septin family.
  • Post-translational
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton > spindle. Chromosome > centromere > kinetochore. Cleavage furrow. Midbody. In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA0128 antibody
    • Nkrf antibody
    • RCG53214, isoform CRA_d antibody
    • RP5-876A24.2 antibody
    • SEP2 antibody
    • SEPT2 antibody
    • SEPT6 antibody
    • SEPT6/MLL FUSION GENE antibody
    • SEPT6_HUMAN antibody
    • Septin 2 antibody
    • Septin 6 antibody
    • Septin-6 antibody
    see all

Anti-SEPT6 antibody images

  • ab106944 (3.8µg/ml) staining of paraffin embedded Human Tonsil following Steamed antigen retrieval with citrate buffer pH 6 and AP-staining shows specific staining in dividing cells just outside a germinal centre.

  • Anti-SEPT6 antibody (ab106944) at 1 µg/ml + Human testis lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 50 kDa

References for Anti-SEPT6 antibody (ab106944)

ab106944 has not yet been referenced specifically in any publications.

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