Overview

  • Product nameAnti-Septin 11 antibody [998C6a]
    See all Septin 11 primary antibodies
  • Description
    Mouse monoclonal [998C6a] to Septin 11
  • Tested applicationsSuitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment corresponsing to a region close to the N-terminus of Human Septin 11

Properties

Applications

Our Abpromise guarantee covers the use of ab84858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 49 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • FunctionFilament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
  • Tissue specificityWidely expressed, except in leukocytes.
  • Involvement in diseaseNote=A chromosomal aberration involving SEPT11 may be a cause of chronic neutrophilic leukemia. Translocation t(4;11)(q21;q23) with MLL/HRX.
  • Sequence similaritiesBelongs to the septin family.
  • Cellular localizationCytoplasm > cytoskeleton. Cell junction > synapse. Cell projection > dendritic spine. Cell projection > axon. Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.
  • Information by UniProt
  • Database links
  • Alternative names
    • SEP11_HUMAN antibody
    • SEPT 11 antibody
    • Sept11 antibody
    • Septin-11 antibody
    • Septin11 antibody
    see all

Anti-Septin 11 antibody [998C6a] images

  • Anti-Septin 11 antibody [998C6a] (ab84858) + immunogen (recombinant fragment of Human protein)

    Predicted band size : 49 kDa

References for Anti-Septin 11 antibody [998C6a] (ab84858)

ab84858 has not yet been referenced specifically in any publications.

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