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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
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Purity IgG fraction
Purification notes Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 40 kDa.Can be blocked with
Human Septin 3 peptide (ab22917).
Use at an assay dependent concentration. PubMed: 17564677
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis.
Tissue specificity Brain-specific.
Sequence similarities Belongs to the septin family.
Post-translational modifications Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.
Cellular localization Cytoplasm. Cytoplasm > cytoskeleton. Cell junction > synapse.
Information by UniProt
Neuronal specific septin 3 antibody
References for Anti-Septin 3 antibody (ab2518)
This product has been referenced in:
et al. Targeted disruption of Sept3, a heteromeric assembly partner of Sept5 and Sept7 in axons, has no effect on developing CNS neurons. J Neurochem 102:77-92 (2007).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"