Anti-SERCA3 ATPase antibody - N-terminal (ab154259)

Overview

  • Product name
    Anti-SERCA3 ATPase antibody - N-terminal
    See all SERCA3 ATPase primary antibodies
  • Description
    Rabbit polyclonal to SERCA3 ATPase - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Chicken, Cow, Xenopus laevis, Xenopus tropicalis
  • Immunogen

    Recombinant fragment, corresponding to a region within N -terminal amino acids 3-185 of Human SERCA3 ATPase (Uniprot ID: Q93084).

  • Positive control
    • Jurkat, Raji, K562 and BCL1 whole cell lysates; Human colon carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab154259 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 114 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
  • Tissue specificity
    Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues.
  • Sequence similarities
    Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
  • Cellular localization
    Nucleus membrane. Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adenosine triphosphatase calcium antibody
    • AT2A3_HUMAN antibody
    • Atp2a3 antibody
    • ATPase Ca(2+) transporting ubiquitous antibody
    • ATPase Ca++ transporting ubiquitous antibody
    • Calcium pump 3 antibody
    • Calcium translocating P type ATPase antibody
    • Sarco/endoplasmic reticulum Ca2+ ATPase antibody
    • Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 antibody
    • SERCA 3 antibody
    • SERCA3 antibody
    • SERCA3b antibody
    • SR Ca(2+) ATPase 3 antibody
    • SR Ca(2+)-ATPase 3 antibody
    see all

Images

  • All lanes : Anti-SERCA3 ATPase antibody - N-terminal (ab154259) at 1/2000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : Raji whole cell lysate
    Lane 3 : K562 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 114 kDa



    5% SDS PAGE
  • Anti-SERCA3 ATPase antibody - N-terminal (ab154259) at 1/5000 dilution + BCL1 whole cell lysate at 30 µg

    Predicted band size: 114 kDa



    5% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human colon carcinoma tissue labeling SERCA3 ATPase with ab154259 at 1/500 dilution.

References

ab154259 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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