Anti-Serine racemase antibody [402CT2.1.2] (ab61335)

Overview

  • Product nameAnti-Serine racemase antibody [402CT2.1.2]
    See all Serine racemase primary antibodies
  • Description
    Mouse monoclonal [402CT2.1.2] to Serine racemase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Human, Cynomolgus Monkey, Macaque Monkey
  • Immunogen

    Recombinant full length human Serine racemase protein.

  • Positive control
    • This antibody gave a positive signal in mouse hippocampus tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab61335 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 5 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

Abcam recommends blocking with 3% Milk.

Target

  • FunctionCatalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
  • Tissue specificityBrain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
  • Sequence similaritiesBelongs to the serine/threonine dehydratase family.
  • Post-translational
    modifications
    S-nitrosylated, leading to decrease the enzyme activity.
  • Information by UniProt
  • Database links
  • Alternative names
    • D serine ammonia lyase antibody
    • D serine dehydratase antibody
    • D-serine ammonia-lyase antibody
    • D-serine dehydratase antibody
    • ILV1 antibody
    • ISO1 antibody
    • L serine ammonia lyase antibody
    • L serine dehydratase antibody
    • L-serine ammonia-lyase antibody
    • L-serine dehydratase antibody
    • Serine racemase antibody
    • srr antibody
    • SRR_HUMAN antibody
    see all

Anti-Serine racemase antibody [402CT2.1.2] images

  • Anti-Serine racemase antibody [402CT2.1.2] (ab61335) at 5 µg/ml + Mouse Hippocampus Tissue Lysate at 20 µg

    Secondary
    Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution

    Performed under reducing conditions.

    Predicted band size : 37 kDa
    Observed band size : 37 kDa
    Additional bands at : 105 kDa,50 kDa,80 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 8 minutes

References for Anti-Serine racemase antibody [402CT2.1.2] (ab61335)

ab61335 has not yet been referenced specifically in any publications.

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