Anti-PI-9 antibody [PI9-17] (ab36624)
Key features and details
- Mouse monoclonal [PI9-17] to PI-9
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG1
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-PI-9 antibody [PI9-17]
See all PI-9 primary antibodies -
Description
Mouse monoclonal [PI9-17] to PI-9 -
Host species
Mouse -
Specificity
Ab36624 recognises Proteinase Inhibitor 9, as well as Proteinase Inhibitor 9 complexed to granzyme B. It shows no cross reactivity with other homologous serpins (PI6, PI8 and PAI2) was observed. -
Tested applications
Suitable for: IHC-P, WBmore details
Unsuitable for: Flow Cyt -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein corresponding to Human PI-9.
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Positive control
- WB: YT-Indy cells (a natural killer leukemia cell line).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.2
Preservative: 0.1% Sodium azide
Constituent: 0.7% BSA
serum free culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
PI9-17 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab36624 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | ||
WB |
Notes |
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WB: Use at an assay dependent dilution. Detects a band of approximately 42, 67 kDa.
Is unsuitable for Flow Cyt.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Granzyme B inhibitor. -
Sequence similarities
Belongs to the serpin family. Ov-serpin subfamily. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 5272 Human
- Omim: 601799 Human
- SwissProt: P50453 Human
- Unigene: 104879 Human
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Alternative names
- CAP 3 antibody
- CAP-3 antibody
- CAP3 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab36624 has been referenced in 2 publications.
- Ibáñez-Molero S et al. SERPINB9 is commonly amplified and high expression in cancer cells correlates with poor immune checkpoint blockade response. Oncoimmunology 11:2139074 (2022). PubMed: 36465485
- El Haddad N et al. The novel role of SERPINB9 in cytotoxic protection of human mesenchymal stem cells. J Immunol 187:2252-60 (2011). Human . PubMed: 21795594