Anti-Serum Amyloid A antibody [38] (ab18707)

Overview

  • Product name
    Anti-Serum Amyloid A antibody [38]
    See all Serum Amyloid A primary antibodies
  • Description
    Mouse monoclonal [38] to Serum Amyloid A
  • Specificity
    ab18707 reacts with recombinant human SAA. It does not show any cross-reaction with other human cytokines or growth factors tested such as IL-1-beta, IL-8, MCAF, TGF-beta and EGF.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly purified human recombinant protein (MW: 12 kDa).

  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab18707 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 12 kDa.

Target

  • Function
    Major acute phase reactant. Apolipoprotein of the HDL complex.
  • Tissue specificity
    Expressed by the liver; secreted in plasma.
  • Involvement in disease
    Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • Sequence similarities
    Belongs to the SAA family.
  • Post-translational
    modifications
    This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amyloid fibril protein AA antibody
    • Amyloid fibrils antibody
    • Amyloid protein A antibody
    • Fibrils antibody
    • MGC111216 antibody
    • OC antibody
    • PIG 4 antibody
    • PIG4 antibody
    • SAA 1 antibody
    • SAA 2 antibody
    • SAA antibody
    • SAA_HUMAN antibody
    • SAA1 antibody
    • SAA2 antibody
    • Serum amyloid A protein precursor antibody
    • Serum amyloid A1 isoform 1 antibody
    • Serum amyloid A1 isoform 2 antibody
    • Serum amyloid protein A(4-101) antibody
    • TP53I4 antibody
    • Tumor protein p53 inducible protein 4 antibody
    see all

References

ab18707 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for your enquiry. The immunogen is a 12 KD recombinant SAA. The size fo SAA1, SAA2 and SAA4 are very similar and there is a possibility that the product can recognize all of them. Unfortunately, we have not confirmed this in the lab and w...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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