Overview

  • Product nameAnti-Serum Amyloid A antibody [3H62]
    See all Serum Amyloid A primary antibodies
  • Description
    Mouse monoclonal [3H62] to Serum Amyloid A
  • SpecificityRecognizes natural and recombinant human SAA. Does not show any crossreactivity with other human cytokines or growth factors tested such as IL-1B, IL-8, MCAF, TGF-B and EGF.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly purified recombinant human SAA, 12kD

Properties

Applications

Our Abpromise guarantee covers the use of ab17758 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 0.1 - 0.5 µg/ml to allow visualization of 100ng/lane of recombinant human SAA. Predicted molecular weight: 14 kDa (unprocessed form).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMajor acute phase reactant. Apolipoprotein of the HDL complex.
    • Tissue specificityExpressed by the liver; secreted in plasma.
    • Involvement in diseaseNote=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
      Note=Elevated serum SSA protein levels may be associated with lung cancer.
    • Sequence similaritiesBelongs to the SAA family.
    • Post-translational
      modifications
      This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Amyloid fibril protein AA antibody
      • Amyloid fibrils antibody
      • Amyloid protein A antibody
      • Fibrils antibody
      • MGC111216 antibody
      • OC antibody
      • PIG 4 antibody
      • PIG4 antibody
      • SAA 1 antibody
      • SAA 2 antibody
      • SAA antibody
      • SAA_HUMAN antibody
      • SAA1 antibody
      • SAA2 antibody
      • Serum amyloid A protein precursor antibody
      • Serum amyloid A1 isoform 1 antibody
      • Serum amyloid A1 isoform 2 antibody
      • Serum amyloid protein A(4-101) antibody
      • TP53I4 antibody
      • Tumor protein p53 inducible protein 4 antibody
      see all

    References for Anti-Serum Amyloid A antibody [3H62] (ab17758)

    This product has been referenced in:
    • Setälä NL  et al. Interaction of phospholipid transfer protein with human tear fluid mucins. J Lipid Res 51:3126-34 (2010). WB ; Human . Read more (PubMed: 20724654) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"