Anti-Serum Amyloid A antibody [607] (ab18711)

Overview

  • Product nameAnti-Serum Amyloid A antibody [607]
    See all Serum Amyloid A primary antibodies
  • Description
    Mouse monoclonal [607] to Serum Amyloid A
  • SpecificityReacts with endogenous and recombinant human SAA. Does not cross-react with other human cytokines or growth factors tested such as IL1ß, IL8, MCAF, TGFß and EGF.
  • Tested applicationsSuitable for: Sandwich ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human).

Properties

Applications

Our Abpromise guarantee covers the use of ab18711 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent concentration. sELISA compatible pair
WB Use a concentration of 0.1 - 0.5 µg/ml. Detects a band of approximately 12 kDa (predicted molecular weight: 14 kDa).

Target

  • FunctionMajor acute phase reactant. Apolipoprotein of the HDL complex.
  • Tissue specificityExpressed by the liver; secreted in plasma.
  • Involvement in diseaseNote=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • Sequence similaritiesBelongs to the SAA family.
  • Post-translational
    modifications
    This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amyloid fibril protein AA antibody
    • Amyloid fibrils antibody
    • Amyloid protein A antibody
    • Fibrils antibody
    • MGC111216 antibody
    • OC antibody
    • PIG 4 antibody
    • PIG4 antibody
    • SAA 1 antibody
    • SAA 2 antibody
    • SAA antibody
    • SAA_HUMAN antibody
    • SAA1 antibody
    • SAA2 antibody
    • Serum amyloid A protein precursor antibody
    • Serum amyloid A1 isoform 1 antibody
    • Serum amyloid A1 isoform 2 antibody
    • Serum amyloid protein A(4-101) antibody
    • TP53I4 antibody
    • Tumor protein p53 inducible protein 4 antibody
    see all

References for Anti-Serum Amyloid A antibody [607] (ab18711)

ab18711 has not yet been referenced specifically in any publications.

Product Wall

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Finally, I have checked the sequence homology between human and horse SAA proteins, the homology is quite low with matching stretches.

http://www.uniprot.org/blast/uniprot/2012101621EV411P6G?alignment=27 Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"