Recombinant
RabMAb

Anti-Serum Amyloid A antibody [EPR11592-129] (ab190801)

Overview

  • Product name
    Anti-Serum Amyloid A antibody [EPR11592-129]
    See all Serum Amyloid A primary antibodies
  • Description
    Rabbit Monoclonal [EPR11592-129] to Serum Amyloid A
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Serum Amyloid A aa 1-100. The exact sequence is proprietary. Sequence is from UniProt P0DJI8 and P0DJI9.
    Database link: P0DJI8

  • Positive control
    • Human serum and plasma lysates; Serum Amyloid A recombinant protein (aa1-122 of UniProt P0DJI9, with a proprietary tag).
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab190801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 12 kDa (predicted molecular weight: 14 kDa).

Target

  • Function
    Major acute phase reactant. Apolipoprotein of the HDL complex.
  • Tissue specificity
    Expressed by the liver; secreted in plasma.
  • Involvement in disease
    Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • Sequence similarities
    Belongs to the SAA family.
  • Post-translational
    modifications
    This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amyloid fibril protein AA antibody
    • Amyloid fibrils antibody
    • Amyloid protein A antibody
    • Fibrils antibody
    • MGC111216 antibody
    • OC antibody
    • PIG 4 antibody
    • PIG4 antibody
    • SAA 1 antibody
    • SAA 2 antibody
    • SAA antibody
    • SAA_HUMAN antibody
    • SAA1 antibody
    • SAA2 antibody
    • Serum amyloid A protein precursor antibody
    • Serum amyloid A1 isoform 1 antibody
    • Serum amyloid A1 isoform 2 antibody
    • Serum amyloid protein A(4-101) antibody
    • TP53I4 antibody
    • Tumor protein p53 inducible protein 4 antibody
    see all

Images

  • All lanes : Anti-Serum Amyloid A antibody [EPR11592-129] (ab190801) at 1/1000 dilution

    Lane 1 : Human serum lysate
    Lane 2 : Human plasma lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

    Predicted band size : 14 kDa
    Observed band size : 12 kDa (why is the actual band size different from the predicted?)
  • Anti-Serum Amyloid A antibody [EPR11592-129] (ab190801) at 1/5000 dilution + Human Serum Amyloid A2 recombinant protein (UniProt P0DJI9) with proprietary tag at 0.01 µg

    Secondary
    Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

    Predicted band size : 14 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)

References

ab190801 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab190801.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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