Anti-Serum Amyloid A antibody [mc1], prediluted (ab43497)

Overview

  • Product name
    Anti-Serum Amyloid A antibody [mc1], prediluted
    See all Serum Amyloid A primary antibodies
  • Description
    Mouse monoclonal [mc1] to Serum Amyloid A, prediluted
  • Specificity
    ab43497 detects amyloid type AA.
  • Tested applications
    Suitable for: IHC-Fr, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified Amyloid A

  • Positive control
    • Kidney with amyloid deposits
  • General notes


    This antibody may be used for the detection of protein deposits (which are not easily detected by HE staining), and will help distinguish between amyloid types AL and B2M. The antibody may also be used for screening purposes in kidney and rectal biopsies.

Properties

  • Form
    Prediluted
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 0.05% BSA, Tissue culture supernatant, PBS, pH 7.3
  • Concentration information loading...
  • Purity
    Tissue culture supernatant
  • Primary antibody notes
    This antibody may be used for the detection of protein deposits (which are not easily detected by HE staining), and will help distinguish between amyloid types AL and B2M. The antibody may also be used for screening purposes in kidney and rectal biopsies.
  • Clonality
    Monoclonal
  • Clone number
    mc1
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab43497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use at an assay dependent concentration.

Use neat.

IHC-P Use at an assay dependent concentration.

Use neat.

Target

  • Function
    Major acute phase reactant. Apolipoprotein of the HDL complex.
  • Tissue specificity
    Expressed by the liver; secreted in plasma.
  • Involvement in disease
    Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • Sequence similarities
    Belongs to the SAA family.
  • Post-translational
    modifications
    This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amyloid fibril protein AA antibody
    • Amyloid fibrils antibody
    • Amyloid protein A antibody
    • Fibrils antibody
    • MGC111216 antibody
    • OC antibody
    • PIG 4 antibody
    • PIG4 antibody
    • SAA 1 antibody
    • SAA 2 antibody
    • SAA antibody
    • SAA_HUMAN antibody
    • SAA1 antibody
    • SAA2 antibody
    • Serum amyloid A protein precursor antibody
    • Serum amyloid A1 isoform 1 antibody
    • Serum amyloid A1 isoform 2 antibody
    • Serum amyloid protein A(4-101) antibody
    • TP53I4 antibody
    • Tumor protein p53 inducible protein 4 antibody
    see all

References

ab43497 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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