Overview

  • Product name
    Anti-serum amyloid A2 antibody
  • Description
    Rabbit polyclonal to serum amyloid A2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Goat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 69-118 (GAWAAEVISN ARENIQRLTG RGAEDSLADQ AANKWGRSGR DPNHFRPAGL) of Human serum amyloid A2 (NP_110381).

  • Positive control
    • 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab125414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 14 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Major acute phase reactant. Apolipoprotein of the HDL complex.
  • Tissue specificity
    Expressed by the liver; secreted in plasma.
  • Involvement in disease
    Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • Sequence similarities
    Belongs to the SAA family.
  • Post-translational
    modifications
    This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amyloid fibril protein AA antibody
    • SAA antibody
    • SAA_HUMAN antibody
    • SAA2 antibody
    • Serum amyloid protein A(4-101) antibody
    see all

Images

  • Anti-serum amyloid A2 antibody (ab125414) at 1 µg/ml + 293T cell lysate at 10 µg

    Predicted band size : 14 kDa

References

ab125414 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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