Overview

  • Product name
  • Description
    Rabbit polyclonal to SESN1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    KLH conjugated synthetic peptide derived between amino acids 21~51 from the N-terminal region of Human SESN1.

  • Positive control
    • Mouse heart tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 57 kDa.

Target

  • Function
    Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Belongs to the sestrin family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110002G11Rik antibody
    • AU044290 antibody
    • MGC118148 antibody
    • MGC138241 antibody
    • MGC142129 antibody
    • OTTMUSP00000022799 antibody
    • p53 activated gene 26 antibody
    • p53 regulated PA26 nuclear protein antibody
    • p53 regulated protein PA26 antibody
    • p53-regulated protein PA26 antibody
    • PA26 antibody
    • RP11-787I22.1 antibody
    • sesn1 antibody
    • SESN1_HUMAN antibody
    • SEST1 antibody
    • sestrin 1 antibody
    • Sestrin-1 antibody
    see all

Images

  • Anti-SESN1 antibody (ab103121) at 1/50 dilution + mouse heart tissue lysates at 35 µg

    Predicted band size : 57 kDa

References

This product has been referenced in:
  • Martin B  et al. GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. Front Endocrinol (Lausanne) 6:191 (2015). Read more (PubMed: 26834700) »
  • Xu B  et al. Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction. Mutat Res 770:1-8 (2014). Read more (PubMed: 25302047) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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