Overview

  • Product name
  • Description
    Rabbit polyclonal to SESN1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    A synthesized peptide derived from an internal region of Human SESN1.

  • Positive control
    • Human breast carcinoma tissue; extracts from Rat muscle cells

Properties

Applications

Our Abpromise guarantee covers the use of ab110483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 57 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Belongs to the sestrin family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110002G11Rik antibody
    • AU044290 antibody
    • MGC118148 antibody
    • MGC138241 antibody
    • MGC142129 antibody
    • OTTMUSP00000022799 antibody
    • p53 activated gene 26 antibody
    • p53 regulated PA26 nuclear protein antibody
    • p53 regulated protein PA26 antibody
    • p53-regulated protein PA26 antibody
    • PA26 antibody
    • RP11-787I22.1 antibody
    • sesn1 antibody
    • SESN1_HUMAN antibody
    • SEST1 antibody
    • sestrin 1 antibody
    • Sestrin-1 antibody
    see all

Anti-SESN1 antibody images

  • All lanes : Anti-SESN1 antibody (ab110483) at 1/500 dilution

    Lane 1 : Extracts from Rat muscle cells
    Lane 2 : Extracts from Rat muscle cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 57 kDa
  • ab110483, at a 1/50 dilution, staining SESN1 in paraffin embedded Human breast carcinoma tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunizing peptide.

References for Anti-SESN1 antibody (ab110483)

ab110483 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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