Overview

  • Product name
  • Description
    Rabbit polyclonal to SESN1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 92-356 of Human SESN1 (Q9Y6P5).

  • Positive control
    • HeLa, HepG2, HCT116 whole cell lysates; Cal27 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab154121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).

Target

  • Function
    Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Belongs to the sestrin family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110002G11Rik antibody
    • AU044290 antibody
    • MGC118148 antibody
    • MGC138241 antibody
    • MGC142129 antibody
    • OTTMUSP00000022799 antibody
    • p53 activated gene 26 antibody
    • p53 regulated PA26 nuclear protein antibody
    • p53 regulated protein PA26 antibody
    • p53-regulated protein PA26 antibody
    • PA26 antibody
    • RP11-787I22.1 antibody
    • sesn1 antibody
    • SESN1_HUMAN antibody
    • SEST1 antibody
    • sestrin 1 antibody
    • Sestrin-1 antibody
    see all

Images

  • Anti-SESN1 antibody (ab154121) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 57 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin embedded Cal27 xenograft tissue labeling SESN1 with ab154121 at 1/500.

References

ab154121 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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