Anti-Sex Hormone Binding Globulin antibody (ab110140)

Overview

  • Product name
    Anti-Sex Hormone Binding Globulin antibody
    See all Sex Hormone Binding Globulin primary antibodies
  • Description
    Goat polyclonal to Sex Hormone Binding Globulin
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to the C terminal region of Sex Hormone Binding Globulin conjugated to KLH

  • Positive control
    • Human placenta tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab110140 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
  • Tissue specificity
    Isoform 1 and isoform 2 are present in liver and testis.
  • Sequence similarities
    Contains 2 laminin G-like domains.
  • Cellular localization
    Secreted. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABP antibody
    • Androgen binding protein antibody
    • SBP antibody
    • Sex hormone-binding globulin antibody
    • Sex steroid binding protein antibody
    • Sex steroid-binding protein antibody
    • SHBG antibody
    • SHBG_HUMAN antibody
    • TeBG antibody
    • Testis specific androgen binding protein antibody
    • Testis-specific androgen-binding protein antibody
    • Testosterone binding beta globulin antibody
    • Testosterone estradiol binding globulin antibody
    • Testosterone estrogen binding globulin antibody
    • Testosterone-estradiol-binding globulin antibody
    • Testosterone-estrogen-binding globulin antibody
    see all

Images

  • ab110140, at 3.75 µg/ml, staining Sex Hormone Binding Globulin in Human placenta tissue by immunohistochemistry. After incubation with ab110140, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

References

ab110140 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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