- Datasheet
- Specific References
- Protocols
Overview
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Product nameAnti-Sez6 antibody
See all Sez6 primary antibodies -
DescriptionRabbit polyclonal to Sez6
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Tested applicationsSuitable for: IHC-Pmore details
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Species reactivityReacts with: Mouse, Human
Predicted to work with: Cow
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Immunogen
Recombinant fragment corresponding to amino acids 774-897 of Human Sez6 (UniProt: Q53EL9).
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Positive control
- Human hippocampus tissue and plasma.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol -
Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab121347 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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FunctionMay play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity.
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Sequence similaritiesBelongs to the SEZ6 family.
Contains 2 CUB domains.
Contains 5 Sushi (CCP/SCR) domains. -
Post-translational
modificationsGlycosylated. -
Cellular localizationCell membrane. Localized on dendrites and in the synaptic and postsynaptic fraction.
- Information by UniProt
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Database links
- Entrez Gene: 539038 Cow
- Entrez Gene: 124925 Human
- Entrez Gene: 20370 Mouse
- SwissProt: A0JNA2 Cow
- SwissProt: Q53EL9 Human
- SwissProt: Q7TSK2 Mouse
- Unigene: 21837 Human
- Unigene: 229330 Mouse
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Alternative names
- Brain-specific receptor-like protein C antibody
- BSRP-C antibody
- hSEZ-6 antibody
see all
Anti-Sez6 antibody images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sez6 antibody (ab121347)This image is courtesy of an Abreview submitted by Hyun Jin Kimab121347 staining Sez6 in Mouse brain tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with paraformaldehyde and blocked with 4% serum for 1 hour at 4°C; antigen retrieval used 0.1% NaBh4. Samples were incubated with primary antibody (undiluted) for 24 hours at 4°C. An undiluted Cy3®-conjugated Goat anti-rabbit IgG polyclonal was used as the secondary antibody.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sez6 antibody (ab121347)ab121347, at 1/25, staining Sez6 in paraffin-embedded Human Hippocampus tissue by Immunohistochemistry.
Protocols
References for Anti-Sez6 antibody (ab121347)
ab121347 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"