• Product nameAnti-SFRP4 antibody
    See all SFRP4 primary antibodies
  • Description
    Goat polyclonal to SFRP4
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Pig
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Human SFRP4.

  • Positive control
    • Human Skeletal Muscle (Interstitial Cells) tissue; Human uterus lysate.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab122905 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
IHC-P Use a concentration of 3.75 µg/ml.


  • FunctionSoluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
  • Tissue specificityExpressed in mesenchymal cells. Highly expressed in the stroma of proliferative endometrium. Expressed in cardiomyocytes. Shows moderate to strong expression in ovarian tumors with expression increasing as the tumor stage increases. In ovarian tumors, expression levels are inversely correlated with expression of CTNNB1 (at protein level).
  • Sequence similaritiesBelongs to the secreted frizzled-related protein (sFRP) family.
    Contains 1 FZ (frizzled) domain.
    Contains 1 NTR domain.
  • DomainThe FZ domain is involved in binding with Wnt ligands.
  • Cellular localizationSecreted. Cytoplasmic in ovarian tumor cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • Frizzled protein antibody
    • Frizzled protein human endometrium antibody
    • FRP 4 antibody
    • FRP4 antibody
    • FrpHE antibody
    • human endometrium antibody
    • Secreted frizzled-related protein 4 antibody
    • sFRP-4 antibody
    • Sfrp4 antibody
    • SFRP4_HUMAN antibody
    see all

Anti-SFRP4 antibody images

  • ab122905, at 3.75 µg/ml, staining SFRP4 in Formalin-fixed, Paraffin-embedded Human Skeletal Muscle (interstitial cells) tissue by Immunohistochemistry.
  • Anti-SFRP4 antibody (ab122905) at 0.3 µg/ml + Human uterus lysate (in RIPA buffer) at 35 µg
    developed using the ECL technique

    Predicted band size : 40 kDa

References for Anti-SFRP4 antibody (ab122905)

This product has been referenced in:
  • Zhang Z  et al. Association of Wnt2 and sFRP4 expression in the third trimester placenta in women with severe preeclampsia. Reprod Sci 20:981-9 (2013). Read more (PubMed: 23322712) »

See 1 Publication for this product

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