Anti-SFRS7 antibody - N-terminal (ab170679)

Overview

  • Product name
    Anti-SFRS7 antibody - N-terminal
    See all SFRS7 primary antibodies
  • Description
    Rabbit polyclonal to SFRS7 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human SFRS7 aa 68-98 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q16629

  • Positive control
    • HeLa cell lysate, formalin fixed and paraffin embedded Human hepatocarcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab170679 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 27 kDa.

Target

  • Function
    Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10.
  • Tissue specificity
    Brain, liver, kidney and lung.
  • Sequence similarities
    Belongs to the splicing factor SR family.
    Contains 1 CCHC-type zinc finger.
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    modifications
    Extensively phosphorylated on serine residues in the RS domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 9G8 antibody
    • AAG3 antibody
    • arginine/serine-rich 7 antibody
    • HSSG1 antibody
    • RBM37 antibody
    • Serine/arginine-rich splicing factor 7 antibody
    • Splicing factor 9G8 antibody
    • Splicing factor antibody
    • Splicing factor, arginine/serine rich 7 antibody
    • SRSF7 antibody
    • SRSF7_HUMAN antibody
    • ZCCHC20 antibody
    • ZCRB2 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed and paraffin embedded Human hepatocarcinoma tissue labeling SFRS7 with ab170679 at 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-SFRS7 antibody - N-terminal (ab170679) at 1/100 dilution + HeLa cell lysate at 35 µg

    Predicted band size: 27 kDa

References

ab170679 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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