Overview

  • Product nameAnti-SFRS9 antibody
    See all SFRS9 primary antibodies
  • Description
    Mouse monoclonal to SFRS9
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Cow, Dog, Pig, Chimpanzee
  • Immunogen

    Recombinant fragment: MSGWADERGG EGDGRIYVGN LPTDVREKDL EDLFYKYGRI REIELKNRHG LVPFAFVRFE DPRDAEDAIY GRNGYDYGQC RLRVEFPRTY GGRGGWPRGG , corresponding to N terminal amino acids 1-101 of Human SFRS9 (NP_003760) linked to a proprietary tag.

  • Positive control
    • Raw 264.7 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1 x PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab88749 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 26 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionPlays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
  • Tissue specificityExpressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.
  • Sequence similaritiesBelongs to the splicing factor SR family.
    Contains 2 RRM (RNA recognition motif) domains.
  • Post-translational
    modifications
    Extensively phosphorylated on serine residues in the RS domain.
  • Cellular localizationNucleus. Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • arginine/serine-rich 9 antibody
    • Pre mRNA splicing factor SRp30C antibody
    • Pre-mRNA-splicing factor SRp30C antibody
    • Serine/arginine-rich splicing factor 9 antibody
    • SFRS 9 antibody
    • Splicing factor antibody
    • Splicing factor arginine/serine rich 9 antibody
    • splicing factor, arginine/serine-rich 9 antibody
    • splicing factor, arginine/serine-rich, 30-KD, C antibody
    • SR splicing factor 9 antibody
    • SRP30C antibody
    • SRSF9 antibody
    • SRSF9_HUMAN antibody
    see all

Anti-SFRS9 antibody images

References for Anti-SFRS9 antibody (ab88749)

ab88749 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Mouse Cell lysate - whole cell (NSC34)
Loading amount 20 µg
Specification NSC34
Gel Running Conditions Reduced Denaturing (4-12% nupage gel)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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Submitted Feb 15 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"