Anti-SGK3 antibody (ab126108)
Key features and details
- Rabbit polyclonal to SGK3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SGK3 antibody
See all SGK3 primary antibodies -
Description
Rabbit polyclonal to SGK3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Chicken, Dog -
Immunogen
Recombinant fragment, corresponding to a region within N terminal amino acids 1-135 of Human SGK3 (Q96BR1).
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Positive control
- IMU32, U-87 MG and MCF7 whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab126108 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 57 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 57 kDa. |
Target
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Function
Involved in the activation of potassium channels. Mediates cell IL-3-dependent survival signals. -
Tissue specificity
Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle. -
Sequence similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain.
Contains 1 PX (phox homology) domain. -
Cellular localization
Cytoplasmic vesicle. Early endosome. Localized in vesicle-like structures and in the early endosome. - Information by UniProt
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Database links
- Entrez Gene: 100533105 Human
- Entrez Gene: 23678 Human
- Entrez Gene: 170755 Mouse
- Omim: 607591 Human
- SwissProt: Q96BR1 Human
- SwissProt: Q9ERE3 Mouse
- Unigene: 613417 Human
- Unigene: 336410 Mouse
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Alternative names
- CISK antibody
- Cytokine independent survival kinase antibody
- DKFZp781N0293 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab126108 has been referenced in 1 publication.
- Yu Q et al. Oxymatrine inhibits the development of non-small cell lung cancer through miR-367-3p upregulation and target gene SGK3 downregulation. Am J Transl Res 12:5538-5550 (2020). PubMed: 33042436