Overview

  • Product nameAnti-SGLT1 antibody
    See all SGLT1 primary antibodies
  • Description
    Goat polyclonal to SGLT1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponsing to internal sequence amino acids of Human SGLT1.

  • Positive control
    • Human small intestine tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab111103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionActively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
  • Tissue specificityExpressed mainly in intestine and kidney.
  • Involvement in diseaseCongenital glucose/galactose malabsorption
  • Sequence similaritiesBelongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • Post-translational
    modifications
    N-glycosylation is not necessary for the cotransporter function.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • D22S675 antibody
    • High affinity sodium glucose cotransporter 1 antibody
    • High affinity sodium glucose cotransporter antibody
    • High affinity sodium-glucose cotransporter antibody
    • Human Na+/glucose cotransporter 1 antibody
    • Na(+)/glucose cotransporter 1 antibody
    • Na+/glucose cotransporter 1 antibody
    • NAGT antibody
    • SC5A1_HUMAN antibody
    • SGLT 1 antibody
    • SGLT1 antibody
    • SLC5A1 antibody
    • Sodium glucose cotransporter 1 antibody
    • Sodium/glucose cotransporter 1 antibody
    • Solute carrier family 5 (sodium/glucose cotransporter) member 1 antibody
    • Solute carrier family 5 member 1 antibody
    see all

Anti-SGLT1 antibody images

  • ab111103, at 3.75µg/ml, staining SGLT1 in formalin-fixed, paraffin-embedded Human small intestine tissue by Immunohistochemistry.

References for Anti-SGLT1 antibody (ab111103)

ab111103 has not yet been referenced specifically in any publications.

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