Overview

  • Product name
  • Description
    Goat polyclonal to SGLT1
  • Tested applications
    Suitable for: WB, IHC-Frmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Chinese hamster
  • Immunogen

    Synthetic peptide:

    C-KDTIEIDAEAPQKEK

    (with a Cysteine residue linker), corresponding to internal sequence amino acids 586-600 of Rat SGLT1 (NP_037165.1).

Properties

Applications

Our Abpromise guarantee covers the use of ab126853 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 73 kDa.
IHC-Fr Use at an assay dependent concentration.

Target

  • Function
    Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
  • Tissue specificity
    Expressed mainly in intestine and kidney.
  • Involvement in disease
    Congenital glucose/galactose malabsorption
  • Sequence similarities
    Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • Post-translational
    modifications
    N-glycosylation is not necessary for the cotransporter function.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • D22S675 antibody
    • High affinity sodium glucose cotransporter 1 antibody
    • High affinity sodium glucose cotransporter antibody
    • High affinity sodium-glucose cotransporter antibody
    • Human Na+/glucose cotransporter 1 antibody
    • Na(+)/glucose cotransporter 1 antibody
    • Na+/glucose cotransporter 1 antibody
    • NAGT antibody
    • SC5A1_HUMAN antibody
    • SGLT 1 antibody
    • SGLT1 antibody
    • SLC5A1 antibody
    • Sodium glucose cotransporter 1 antibody
    • Sodium/glucose cotransporter 1 antibody
    • Solute carrier family 5 (sodium/glucose cotransporter) member 1 antibody
    • Solute carrier family 5 member 1 antibody
    see all

Images

  • All lanes : Anti-SGLT1 antibody (ab126853) at 2.5 µg/ml

    Lane 1 : Brush-border membranes from Rat Kidney.
    Lane 2 : Brush-border membranes from Rat Kidney.

    Developed using the ECL technique

    Predicted band size : 73 kDa
  • ab126853 (25ug/ml) IHC staining of cryosections of Rat Kidney. Detection by CY3 fluorescence.


  • Predicted band size : 73 kDa
  • ab126853 (25ug/ml) IHC staining of cryosections of Rat Small Intestines. Detection by CY3 fluorescence.

References

ab126853 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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