The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesPeptide ELISA: antibody detection limit dilution 1/1000
WB: Use at a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 53 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionInhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
Tissue specificityUbiquitously expressed. Aberrantly expressed in some cancers.
Sequence similaritiesContains 1 SH2 domain.
Cellular localizationCytoplasm. Located at podocyte foot processes.