Overview

  • Product name
  • Description
    Goat polyclonal to SH2D4A
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide:

    C-HQKKESMKKKQDE

    , corresponding to internal sequence amino acids 197 - 209 of Human SH2D4A (NP_071354.2)

  • Positive control
    • Human Kidney lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab80606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    Peptide ELISA: antibody detection limit dilution 1/1000
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 53 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
    • Tissue specificity
      Ubiquitously expressed. Aberrantly expressed in some cancers.
    • Sequence similarities
      Contains 1 SH2 domain.
    • Cellular localization
      Cytoplasm. Located at podocyte foot processes.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ20967 antibody
      • PPP1R38 antibody
      • Protein phosphatase 1 regulatory subunit 38 antibody
      • Protein SH antibody
      • Protein SH(2)A antibody
      • Protein SH2A antibody
      • SH2 domain containing 4A antibody
      • SH2 domain containing protein 4A antibody
      • SH2 domain-containing protein 4A antibody
      • SH24A_HUMAN antibody
      • SH2A antibody
      • Sh2d4a antibody
      see all

    Images

    • Anti-SH2D4A antibody (ab80606) at 0.1 µg/ml + Human Kidney lysate (in RIPA buffer) at 35 µg

      Predicted band size : 53 kDa
      Observed band size : 53 kDa

    References

    ab80606 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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