For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
- PurityImmunogen affinity purified
- Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography
- Research areas
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 41 kDa.
- FunctionImplicated in endocytosis. May recruit other proteins to membranes with high curvature.
- Tissue specificityUbiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.
- Involvement in diseaseNote=In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.
- Sequence similaritiesBelongs to the endophilin family.
Contains 1 BAR domain.
Contains 1 SH3 domain.
- DomainAn N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.
- Cellular localizationCytoplasm. Early endosome membrane. Associated with postsynaptic endosomes in hippocampal neurons.
Information by UniProt
- CNSA1 antibody
- EEN antibody
- EEN fusion partner of MLL antibody
Anti-SH3 containing Grb 2 like 1 protein antibody images
References for Anti-SH3 containing Grb 2 like 1 protein antibody (ab113419)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"