Anti-SH3 containing Grb 2 like 1 protein antibody (ab86605)


  • Product name
    Anti-SH3 containing Grb 2 like 1 protein antibody
    See all SH3 containing Grb 2 like 1 protein primary antibodies
  • Description
    Rabbit polyclonal to SH3 containing Grb 2 like 1 protein
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog, Chimpanzee, Ferret, Rhesus monkey, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between residues 225 and 275 of human SH3 containing Grb 2 like 1 protein (NP_003016.1)

  • Positive control
    • HeLa whole cell lysate.


  • Form
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab86605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
IP Use at 2-5 µg/mg of lysate.


  • Function
    Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
  • Tissue specificity
    Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.
  • Involvement in disease
    Note=In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.
  • Sequence similarities
    Belongs to the endophilin family.
    Contains 1 BAR domain.
    Contains 1 SH3 domain.
  • Domain
    An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes.
  • Cellular localization
    Cytoplasm. Early endosome membrane. Associated with postsynaptic endosomes in hippocampal neurons.
  • Information by UniProt
  • Database links
  • Alternative names
    • CNSA1 antibody
    • EEN antibody
    • EEN fusion partner of MLL antibody
    • Endophilin-2 antibody
    • Endophilin-A2 antibody
    • Extra 11 19 leukemia fusion gene antibody
    • Extra eleven-nineteen leukemia fusion gene protein antibody
    • Fusion partner of MLL antibody
    • MGC111371 antibody
    • SH3 containing Grb 2 like 1 protein antibody
    • SH3 containing protein EEN antibody
    • SH3 domain GRB2 like 1 antibody
    • SH3 domain protein 2B antibody
    • SH3 domain-containing GRB2-like protein 1 antibody
    • SH3D2B antibody
    • SH3G1_HUMAN antibody
    • Sh3gl1 antibody
    • SH3P8 antibody
    see all

Anti-SH3 containing Grb 2 like 1 protein antibody images

  • All lanes : Anti-SH3 containing Grb 2 like 1 protein antibody (ab86605) at 0.04 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg

    Predicted band size : 41 kDa

    Exposure time : 30 seconds
  • Detection of SH3 containing Grb 2 like 1 protein by Western Blot of Immunprecipitate.
    ab86605 at 1µg/ml staining SH3 containing Grb 2 like 1 protein in HeLa whole cell lysate immunoprecipitated using ab86605 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 10 seconds.

References for Anti-SH3 containing Grb 2 like 1 protein antibody (ab86605)

ab86605 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab86605.
Please use the links above to contact us or submit feedback about this product.


Sign up