Overview

  • Product nameAnti-SH3BP1 antibody
    See all SH3BP1 primary antibodies
  • Description
    Rabbit polyclonal to SH3BP1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Cow, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 126-174 of Human SH3BP1 according to NP_061830.3

  • Positive control
    • 721_B cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 76 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionBinds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
  • Sequence similaritiesContains 1 BAR domain.
    Contains 1 Rho-GAP domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3BP 1 antibody
    • 3BP-1 antibody
    • 3BP1_HUMAN antibody
    • ARHGAP43 antibody
    • dJ37E16 antibody
    • FLJ21318 antibody
    • OTTHUMP00000028981 antibody
    • SH3 domain binding protein 1 antibody
    • SH3 domain-binding protein 1 antibody
    • Sh3bp1 antibody
    see all

Anti-SH3BP1 antibody images

  • Anti-SH3BP1 antibody (ab118760) at 1 µg/ml + 721 B cell lysate at 10 µg

    Predicted band size : 76 kDa

References for Anti-SH3BP1 antibody (ab118760)

ab118760 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"