Overview

  • Product nameAnti-SH3BP2 antibody
    See all SH3BP2 primary antibodies
  • Description
    Mouse monoclonal to SH3BP2
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 452-561 of Human SH3BP2

Properties

Applications

Our Abpromise guarantee covers the use of ab55696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 62 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • FunctionBinds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
  • Tissue specificityExpressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas.
  • Involvement in diseaseDefects in SH3BP2 are the cause of cherubism (CRBM) [MIM:118400]. CRBM is an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws, which often begins around three years of age. It is followed by development of fibrous tissue masses, which causes a characteristic facial swelling.
  • Sequence similaritiesContains 1 PH domain.
    Contains 1 SH2 domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3BP-2 antibody
    • 3BP2 antibody
    • 3BP2_HUMAN antibody
    • Abl SH3 binding protein 2 antibody
    • Cherubism antibody
    • CRBM antibody
    • CRPM antibody
    • FLJ42079 antibody
    • FLJ54978 antibody
    • RES4-23 antibody
    • SH3 domain binding protein 2 antibody
    • SH3 domain-binding protein 2 antibody
    • Sh3bp2 antibody
    • TNFAIP3 interacting protein 2 antibody
    see all

Anti-SH3BP2 antibody images



  • Predicted band size : 62 kDa
    SH3BP2 antibody (ab55696) at 1ug/lane + A-431 cell lysate at 25ug/lane.
  • ab55696 at 10 ug/ml staining SH3BP2 in human Hella cells by Immunocytochemistry/ Immunofluorescence.

References for Anti-SH3BP2 antibody (ab55696)

ab55696 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"