Overview

  • Product nameAnti-SH3BP4 antibody
    See all SH3BP4 primary antibodies
  • Description
    Rabbit polyclonal to SH3BP4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 (FTTLKFSKGD HLYVLDTSGG EWWYAHNTTE MGYIPSSYVQ PLNYRNSTLS) of Human SH3BP4 (NP_055336).

  • Positive control
    • ACHN cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab102543 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 107 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionFunctions in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis.
  • Tissue specificityExpressed in all tissues tested with higher expression in pancreas. Expressed by retinal pigment epithelial cells (at protein level).
  • Sequence similaritiesContains 1 SH3 domain.
  • DomainThe SH3 domain mediates localization to the clathrin-coated pits and vesicles. The SH3 domain mediates interaction with DNM2 and the cytoplasmic part of TFRC with a lower affinity.
  • Post-translational
    modifications
    Phosphorylated upon EGF stimulation. Phosphorylation prevents interaction with DNM2.
  • Cellular localizationMembrane > clathrin-coated pit. Cytoplasmic vesicle > clathrin-coated vesicle. Nucleus. Specifically associated with transferrin receptor-containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • BOG25 antibody
    • EH binding protein antibody
    • EH binding protein 10 antibody
    • EH-binding protein 10 antibody
    • EHB10 antibody
    • SH3 domain binding protein 4 antibody
    • SH3 domain-binding protein 4 antibody
    • SH3B4_HUMAN antibody
    • sh3bp4 antibody
    • Transferrin receptor trafficking protein antibody
    • Transferrin receptor-trafficking protein antibody
    • TTP antibody
    see all

Anti-SH3BP4 antibody images

  • Anti-SH3BP4 antibody (ab102543) at 1 µg/ml + ACHN cell lysate at 10 µg

    Predicted band size : 107 kDa

References for Anti-SH3BP4 antibody (ab102543)

ab102543 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"